When oxygen was low, MOTS-c treated diabetic rat hearts used less ATP, which may help protect the heart during low-oxygen events like heart attacks.

14

Pro

0

Against

Evidence from Studies

Supporting (1)

14

Community contributions welcome

14

Mitochondria-derived peptide MOTS-c restores mitochondrial respiration in type 2 diabetic heart

Randomized Controlled Trial

Animal

2025

Contradicting (0)

0

Community contributions welcome

No contradicting evidence found

Source Study

Mitochondria-derived peptide MOTS-c restores mitochondrial respiration in type 2 diabetic heart

Score: 14

DOI: 10.3389/fphys.2025.1602271

Similar Assertions

Diabetic rats had weaker heart mitochondria energy production, but MOTS-c treatment helped improve it back to normal levels.

14

0

81%

Diabetic rats given MOTS-c had lower blood sugar levels after fasting, showing better control of glucose.

14

0

73%

Heart cells from diabetic rats have weaker power plants that leak more harmful molecules than those from healthy rats, which matches what scientists expect in diabetes-related heart damage.

0

10

70%