When people don't eat for 3 days, their noradrenaline levels go up, but not until after the second day of fasting.
Scientific Claim
During acute starvation in healthy young adults, plasma noradrenaline levels increase significantly only after 72 hours, with no change at 36 hours, indicating a delayed sympathetic nervous system response to prolonged fasting.
Original Statement
“Plasma noradrenaline levels changed with starvation (Fig. 4; time effect P < 0.001, ANOVA). There was no change in levels at 36 h compared with those at 12 h (P= 0.89), but the levels at 72 h were significantly greater than those at both 12 and 36 h (P= 0.002 and P < 0.001 respectively).”
Evidence Quality Assessment
Claim Status
appropriately stated
Study Design Support
Design supports claim
Appropriate Language Strength
association
Can only show association/correlation
Assessment Explanation
The study design (cohort study) can describe associations between starvation and physiological changes. The claim uses 'increase' which appropriately reflects the observed association.
Evidence from Studies
Supporting (1)
The cardiovascular, metabolic and hormonal changes accompanying acute starvation in men and women