When people eat only until 2 p.m., their bodies break down more protein during the day, probably to make glucose while fasting.

Scientific Claim

Early time-restricted feeding increases 24-hour protein oxidation by 13 ± 4 g/day in overweight adults, likely due to enhanced gluconeogenesis during prolonged fasting.

Original Statement

“eTRF increased 24-hour protein oxidation by Δ=13±4 g/day (85±15 vs. 71±11 g/day; p=0.009).”

From study:Early Time-Restricted Feeding Reduces Appetite and Increases Fat Oxidation but Does Not Affect Energy Expenditure in Humans

Evidence Quality Assessment

Claim Status

appropriately stated

Study Design Support

Design supports claim

Appropriate Language Strength

definitive

Can make definitive causal claims

Assessment Explanation

The RCT design with direct biochemical measurement supports definitive causal language. The effect size and p-value are clearly reported and mechanistically plausible.

Evidence from Studies

Supporting (0)

No supporting evidence found

Contradicting (1)

Early Time-Restricted Feeding Reduces Appetite and Increases Fat Oxidation but Does Not Affect Energy Expenditure in Humans

Randomized Controlled Trial

Human

2019 Aug

This study found that eating earlier in the day makes people less hungry and burns more fat, but it didn’t measure or find any change in how much protein the body breaks down, so it doesn’t support the claim about protein oxidation.

Source Study

Early Time-Restricted Feeding Reduces Appetite and Increases Fat Oxidation but Does Not Affect Energy Expenditure in Humans

Score: 65

DOI: 10.1002/oby.22518

Similar Assertions

When people eat only between 8 a.m. and 2 p.m., their bodies burn more fat, especially at night, as shown by a measurable drop in a metabolic marker called npRQ.

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After four days of eating only until 2 p.m., people lost a tiny bit of weight—about half a pound—mostly from water and stored carbs, not fat.

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When healthy young men only eat between noon and 8pm for five days straight, their bodies burn fat much faster while they're fasting compared to when they eat throughout the day

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When healthy young men only eat between noon and 8pm for five days straight, it doesn't change how much carbohydrate their bodies burn while fasting

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