When rats' eye tissue was treated with an enzyme that breaks down collagen, the stiffness of the outer part of the eye decreased by almost 40% compared to normal.

After damaging the eye tissue with enzymes, adding a saline solution (vehicle) made the stiffness drop even more by about 26% compared to the damaged state.

After damaging the eye tissue with collagen-breaking enzymes, applying a special peptide helped restore some stiffness, increasing it by about 23% compared to the damaged state.

In the inner part of the eye's optic nerve head, collagen-breaking enzymes caused a 57% drop in stiffness compared to normal.