When researchers looked at the ovaries of rats under a microscope, they saw less evidence of cell death signals in the rats that received shilajit before radiation compared to rats that only got radiation.
Scientific Claim
Shilajit administration at 25 mg/kg/day for 4 days before radiation exposure was associated with reduced intensity of apoptotic protein expression (p53, Bax, and caspase 3) in rat ovarian follicles compared to radiation exposure alone, with the radiation + shilajit group showing less intense staining for these markers than the radiation-only group.
Source Excerpt
“In radiation + shilajit group, p53, Bax and caspase 3 expression was less intense than that in the radiation only group follicles.”
Evidence from Studies
Supporting Studies
Evaluation of preventive effect of shilajit on radiation-induced apoptosis on ovaries
The study used immunohistopathological analysis to quantify expression of key apoptotic proteins. The radiation + shilajit group showed visibly less intense staining for p53, Bax, and caspase 3 compared to the radiation-only group, indicating reduced activation of the apoptotic pathway.