The Claim

In women aged 44–60 using topical tretinoin, adjunctive application of Mineral 89 Probiotic Fractions® for 28 days significantly improved skin hydration by 11.5% compared to baseline, while the untreated side showed no significant change, indicating that Mineral 89 Probiotic Fractions® enhances epidermal water retention during retinoid therapy.

Source: Benefits of the Dermocosmetic Mineral 89 Probiotic Fractions Adjunct to Topical Retinoids for Anti-Aging Benefits

What the research says

Supports is higher

Support is ahead, but a single strong opposing study can change this.

Supports
61score
Challenges
0score

These are independent scores, not a percentage. Higher-grade studies count more, so a single strong opposing study can outweigh several weaker ones.

Cause and effect
1 study reviewed
In plain English

In women aged 44–60 using tretinoin cream, applying Mineral 89 Probiotic Fractions® on one side of the face for 28 days increased skin hydration by 11.5% compared to the untreated side, which showed no change.

See the scientific wording

In women aged 44–60 using topical tretinoin, adjunctive application of Mineral 89 Probiotic Fractions® for 28 days significantly improved skin hydration by 11.5% compared to baseline, while the untreated side showed no significant change, suggesting M89PF enhances epidermal water retention during retinoid therapy.

Why this might work

A special moisturizer with minerals, hyaluronic acid, niacinamide, and vitamin E is applied to the skin. Hyaluronic acid pulls water into the outer skin layer, making it plump and moist. Niacinamide stops inflammatory signals that cause redness and irritation. Vitamin E protects skin cells from damage caused by free radicals. Minerals help repair the skin’s natural protective layer. Together, these ingredients prevent water loss and calm the skin, allowing it to hold more moisture even when a retinoid is being used.

Verified mechanismbased on 1 study

What the research says

1 study

  1. Study: Benefits of the Dermocosmetic Mineral 89 Probiotic Fractions Adjunct to Topical Retinoids for Anti-Aging Benefits

    When women in their 40s to 60s used a special moisturizer alongside their retinoid cream, their skin got noticeably more hydrated after four weeks — but the side without the moisturizer didn’t improve. So the moisturizer helped keep skin moist while using the retinoid.

Score breakdown, mechanism chain, raw evidence, ideal studies needed & 1 supporting studies

Fit Body Science verdict — we translate health claims into clear verdicts backed by peer-reviewed research.

Not medical advice. For informational purposes only. Always consult a qualified healthcare professional before making health decisions.