The Claim
In women aged 44–60 using nightly 0.025% tretinoin for 84 days, adjunctive twice-daily application of Mineral 89 Probiotic Fractions® for 28 days reduces facial erythema by 70% and improves skin hydration by 11.5% compared to tretinoin and sunscreen alone, with additional improvements in fine lines, skin tone, radiance, and pore appearance observed by day 84.
What the research says
Supports is higher
Support is ahead, but a single strong opposing study can change this.
These are independent scores, not a percentage. Higher-grade studies count more, so a single strong opposing study can outweigh several weaker ones.
Women aged 44–60 who applied Mineral 89 Probiotic Fractions® twice daily for 28 days while using tretinoin and sunscreen experienced a 70% reduction in facial redness and an 11.5% increase in skin hydration compared to those using only tretinoin and sunscreen. Additional improvements in fine lines, skin tone, radiance, and pore appearance were observed after 84 days.
See the scientific wording
In women aged 44–60 using nightly 0.025% tretinoin for 84 days, adjunctive application of Mineral 89 Probiotic Fractions® (M89PF) twice daily for 28 days significantly reduced facial erythema by 70% and improved skin hydration by 11.5% compared to tretinoin and sunscreen alone, with further improvements in fine lines, skin tone, radiance, and pore appearance observed by day 84, suggesting M89PF enhances short-term tolerability and visible skin appearance during retinoid therapy.
A moisturizer with minerals, hyaluronic acid, niacinamide, and vitamin E is applied to the skin. Hyaluronic acid pulls water into the outer skin layer, making it plump and less cracked. Niacinamide stops chemicals that cause redness and swelling from being released. Vitamin E neutralizes harmful molecules created by the retinoid. Minerals help repair the skin’s protective layer. Together, these ingredients reduce the signals that trigger redness and dryness, allowing the skin to heal faster while the retinoid works.
What the research says
1 studyWhen women in their 40s to 60s use a strong anti-aging cream (tretinoin) that can cause redness and dryness, adding this special moisturizer with minerals and hydrating ingredients makes their skin less irritated and look better faster — better than using just the cream and sunscreen.
Score breakdown, mechanism chain, raw evidence, ideal studies needed & 1 supporting studies
Not medical advice. For informational purposes only. Always consult a qualified healthcare professional before making health decisions.