Whether you lift light weights or heavy weights until you can't do another rep, your slow-twitch muscle fibers in your thighs grow about the same amount — but we can't be sure because the results are too uncertain.

Lifting light or heavy weights until failure doesn’t clearly make your fast-twitch muscle fibers bigger in your thighs — the data is too mixed to say one is better.

Whether you lift light weights or heavy weights until you can’t do another rep, your muscle fibers don’t seem to grow significantly more with one than the other — but we can’t be sure because the results are too uncertain.

We can’t say whether light or heavy weights are better for growing muscle fibers in the thighs — we just don’t have enough good data yet, and we need more studies with more people.

We just don’t know yet if light or heavy weights make muscles grow better — the results could swing either way in future studies, so we need more research.

If you're a young man who already lifts weights, doing workouts with either light weights (lots of reps) or heavy weights (fewer reps)—as long as you push yourself until you can't do another rep—will make your muscles grow just as much either way.