In women aged 44–60 using topical tretinoin, adjunctive use of Mineral 89 Probiotic Fractions® for 84 days significantly improved Dermatology Life Quality Index (DLQI) and Skindex-16 scores.

A moisturizing formula with specific minerals, hyaluronic acid, niacinamide, and vitamin E is applied to the skin. Hyaluronic acid pulls water into the outer skin layer, making it plumper and less cracked. Niacinamide stops inflammatory signals from spreading, reducing redness and stinging. Vitamin E neutralizes harmful molecules created by the acne medication. Minerals in the formula support the skin’s natural repair systems. The probiotic components shift the skin’s immune response away from inflammation by increasing a natural blocker of inflammation and reducing a key inflammatory trigger. This stops the cycle of dryness, burning, and itching, so the skin feels better and people feel less distressed by their appearance.