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Back to Study: Esterified estrogens and conjugated equine estroge...
correlational
Analysis v1
Strong Support

Women who take both estrogen and progestin together have a 60% higher chance of developing blood clots in their veins than women who take estrogen alone.

55
Pro
0
Against

Evidence from Studies

Supporting (1)

55

Community contributions welcome

55

Esterified estrogens and conjugated equine estrogens and the risk of venous thrombosis.

Case-Control Study
Human
2004 Oct 6

The study found that women who took both estrogen and progestin had a 60% higher chance of developing blood clots than those who took estrogen alone — which is exactly what the claim says.

Contradicting (0)

0

Community contributions welcome

No contradicting evidence found

Gold Standard Evidence Needed

According to GRADE and EBM methodology, here is what ideal scientific evidence would look like to definitively prove or disprove this specific claim, ordered from strongest to weakest evidence.

Source Study

Esterified estrogens and conjugated equine estrogens and the risk of venous thrombosis.

Score: 55
DOI: 10.1001/jama.292.13.1581

Similar Assertions

Women who are going through or have passed menopause and are taking a specific type of hormone pill called esterified estrogen aren’t more likely to get a dangerous blood clot for the first time than women who aren’t taking any hormones.

55
0
81%

Women who take a type of hormone therapy called conjugated equine estrogen are 78% more likely to develop blood clots in their veins than women who take a different type called esterified estrogen.

55
0
78%

If you use a patch or gel for estrogen instead of a pill, and pair it with a specific type of progesterone, you’re not more likely to get dangerous blood clots — but if you take estrogen as a pill with any progesterone, your risk of blood clots doubles compared to not taking any hormones at all.

1
0
76%

Women who take higher doses of this hormone medicine called conjugated equine estrogen are more likely to develop blood clots in their veins.

55
0
76%

Women who are going through or have passed menopause and are taking a specific type of hormone pill called conjugated equine estrogen are 65% more likely to have their first blood clot in a vein than women who aren’t taking any hormones.

55
0
74%