Analysis Version
v1
History
Back to Study: Esterified estrogens and conjugated equine estroge...
correlational
Analysis v1
Strong Support

Women who take higher doses of this hormone medicine called conjugated equine estrogen are more likely to develop blood clots in their veins.

55
Pro
0
Against

Evidence from Studies

Supporting (1)

55

Community contributions welcome

55

Esterified estrogens and conjugated equine estrogens and the risk of venous thrombosis.

Case-Control Study
Human
2004 Oct 6

This study found that women who took higher doses of a specific type of estrogen pill (conjugated equine estrogen) were more likely to get dangerous blood clots than those who took lower doses, which matches exactly what the claim says.

Contradicting (0)

0

Community contributions welcome

No contradicting evidence found

Gold Standard Evidence Needed

According to GRADE and EBM methodology, here is what ideal scientific evidence would look like to definitively prove or disprove this specific claim, ordered from strongest to weakest evidence.

Source Study

Esterified estrogens and conjugated equine estrogens and the risk of venous thrombosis.

Score: 55
DOI: 10.1001/jama.292.13.1581

Similar Assertions

Women who are going through or have passed menopause and are taking a specific type of hormone pill called conjugated equine estrogen are 65% more likely to have their first blood clot in a vein than women who aren’t taking any hormones.

55
0
91%

Women who take a type of hormone therapy called conjugated equine estrogen are 78% more likely to develop blood clots in their veins than women who take a different type called esterified estrogen.

55
0
91%

Taking Premarin for hormone therapy might make you more likely to get dangerous blood clots than taking a different type of estrogen called bio-identical estradiol.

55
0
80%

Some women take hormones to manage menopause symptoms, and this claim says that a type of estrogen made to match the body’s own (bio-identical estradiol) is safer for blood clots than a different type made from horse urine (conjugated equine estrogens).

1
0
79%

Women who take both estrogen and progestin together have a 60% higher chance of developing blood clots in their veins than women who take estrogen alone.

55
0
76%