Women who take a type of hormone therapy called conjugated equine estrogen are 78% more likely to develop blood clots in their veins than women who take a different type called esterified estrogen.

55

Pro

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Against

Evidence from Studies

Supporting (1)

55

Community contributions welcome

55

Esterified estrogens and conjugated equine estrogens and the risk of venous thrombosis.

Case-Control Study

Human

2004 Oct 6

This study found that women taking conjugated equine estrogen were about 78% more likely to get blood clots than those taking esterified estrogen, which is exactly what the claim says.

Contradicting (0)

0

Community contributions welcome

No contradicting evidence found

Gold Standard Evidence Needed

According to GRADE and EBM methodology, here is what ideal scientific evidence would look like to definitively prove or disprove this specific claim, ordered from strongest to weakest evidence.

Source Study

Esterified estrogens and conjugated equine estrogens and the risk of venous thrombosis.

Score: 55

DOI: 10.1001/jama.292.13.1581

Similar Assertions

Women who take higher doses of this hormone medicine called conjugated equine estrogen are more likely to develop blood clots in their veins.

55

0

91%

Women who are going through or have passed menopause and are taking a specific type of hormone pill called conjugated equine estrogen are 65% more likely to have their first blood clot in a vein than women who aren’t taking any hormones.

55

0

90%

Some women take hormones to manage menopause symptoms, and this claim says that a type of estrogen made to match the body’s own (bio-identical estradiol) is safer for blood clots than a different type made from horse urine (conjugated equine estrogens).

1

0

82%

Taking Premarin for hormone therapy might make you more likely to get dangerous blood clots than taking a different type of estrogen called bio-identical estradiol.

55

0

80%

Women who take both estrogen and progestin together have a 60% higher chance of developing blood clots in their veins than women who take estrogen alone.

55

0

78%