Health Claims

Medicines like semaglutide and tirzepatide help people lose a lot of weight—up to a quarter of their body weight—but they also cause some muscle loss, about as much as you’d normally lose in 10 years of aging.

Taking GLP-1 drugs might help your muscles stay strong even as you lose weight, by improving how your body uses insulin and reducing fat buildup in the muscles.

If you're older or not very physically strong to begin with, taking certain weight-loss drugs like GLP-1 agonists might increase your risk of losing muscle. So doctors should think about your age and fitness level before prescribing these drugs.

When adults lose weight using GLP-1 drugs like Ozempic, their muscles seem to change in a healthy way — not losing strength or quality, and possibly even improving how they work.

When people with obesity take retatrutide, the most common side effects are stomach problems like nausea or diarrhea. These tend to happen more and get worse when the dose is higher, but starting with a lower dose (2 mg) might help reduce these issues.

Most people with obesity who take a high dose of a drug called retatrutide every week for nearly a year lose at least 15% of their body weight — that’s like dropping 30 pounds if you weigh 200. Almost no one on a fake pill loses that much.

People with obesity who took a shot called retatrutide once a week for a year lost nearly a quarter of their body weight—way more than those who got a dummy shot. This makes it one of the strongest weight-loss medicines we’ve seen so far.

When people get stuck at a weight loss plateau, there's no one-size-fits-all fix—experts say the best approach depends on the person because everyone's body and habits respond differently.

Some strict diets like high-protein, keto, or very low-calorie plans might help people get past weight loss stalls — but only with a doctor's help. They’re not meant for everyone or for long-term use because we don’t fully know how safe or effective they are over time.

If you're stuck at the same weight even though you're eating right and working out, moving more throughout the day—like fidgeting, standing, or walking—and checking for hidden health issues might help you start losing weight again.

If you're stuck at a weight loss plateau, changing your diet mix, timing your eating, and mixing cardio with strength training might help you start losing fat again by working with your body's natural rhythms and habits.

When adults try to lose weight, they often hit a plateau — where the scale stops moving — even if they're still eating less and exercising. This happens because the body changes how it burns calories, hormones shift, and motivation can fade, making it really hard to keep losing weight without extra help.

People with obesity or type 2 diabetes who take a drug called retatrutide are more likely to get stomach issues like nausea, throwing up, or constipation—especially if they take higher doses (8 or 12 mg per week). But most people don’t have to stop taking it because of serious side effects.

Taking a drug called retatrutide once a week might lower blood pressure in people with obesity or type 2 diabetes, which could help protect their heart over time.

This drug called retatrutide probably helps people with obesity or type 2 diabetes control their blood sugar better, especially if they take a higher dose.

Taking a drug called retatrutide every week for about 6 to 12 months probably helps people with obesity or type 2 diabetes lose belly fat and drop their BMI by noticeable amounts.

Adults with obesity or type 2 diabetes who take a weekly 12 mg dose of retatrutide are way more likely—over 70 times more—to lose at least 15% of their body weight in less than a year compared to those taking a fake pill.

A drug called retatrutide probably helps people with obesity or type 2 diabetes lose about 14% of their body weight when given as a weekly shot for up to a year, and higher doses seem to lead to more weight loss.

When people take liraglutide for weight loss, their brain's 'decision-making' area might become more active as a way to push back against further weight loss — which could be why the pounds stop dropping after a while.

Taking the drug liraglutide at 3.0 mg might help people with obesity better control their impulses, like stopping themselves from doing something quickly, even if their reaction speed didn't clearly improve.

When people with obesity take a weight-loss drug called liraglutide for 5 weeks, their brain's food-reward area becomes more active when they see food — even after accounting for weight loss, which might mean the brain is fighting back against losing weight.

If someone is obese and takes a weight-loss drug called liraglutide for 5 weeks, their brain doesn’t react differently to pictures of food — at least not if we don’t factor in how much weight they lost.

If you're an obese adult, taking a daily injection of liraglutide for 5 weeks might help you lose about 2.7% more weight than if you took a fake pill, and it could also lower your blood sugar, bad cholesterol, and waist size — plus you might naturally eat less fat and fewer calories.

Retatrutide, a diabetes drug, helped nearly 6 out of 10 adults lose at least 15% of their body weight in less than a year — way more than another drug called dulaglutide, which only helped 2 out of 10 people hit that goal.