Browse evidence-based analysis of health-related claims and assertions
Mice that are missing a certain brain signaling system have weaker daily rhythms in their thyroid gland, which suggests this system helps keep the body's internal clock running strongly in that organ.
Even when the brain's main body clock loses its rhythm, the thyroid gland in mice can still keep its own daily rhythm going — suggesting it doesn’t completely depend on signals from the brain’s clock center.
There's a computer model that can mimic how our thyroid hormones rise and fall during the day, and it works by timing how the body converts one hormone into another in different places, with the body's tissues getting a 3-hour head start over the thyroid gland.
The body’s internal system that turns one thyroid hormone into another isn’t enough on its own to explain the timing and levels of these hormones throughout the day.
Your body's daily rhythm of thyroid hormones isn't caused by just one thing—like the thyroid working on a schedule or how the hormone moves through your blood. It's more complicated than that.
Dogs with an underactive thyroid tend to have more belly fat, which might make their bodies less responsive to insulin, but their stress hormone levels don’t seem to go up.
Dogs with an underactive thyroid might have higher levels of certain growth hormones, which could make their bodies less responsive to insulin.
Dogs with artificially lowered thyroid levels still process sugar normally, and their insulin system works just as well as healthy dogs.
Dogs with artificially lowered thyroid function become less responsive to insulin, so their bodies make more insulin to keep blood sugar under control.
These three drugs don’t block the pituitary’s response to a brain signal that turns on the thyroid, so they probably stop the signal earlier—right in the brain—when it comes to cold-triggered thyroid activity.
When animals get cold, their brain tells their thyroid to speed up their metabolism through nerve signals, and certain drugs can block this — showing it's controlled by the nervous system.
The way your body handles stress might change in conditions like chronic fatigue and fibromyalgia — and that change could actually be your body trying to cope, not something broken.
People with chronic fatigue or fibromyalgia often have low cortisol, but it's not because their brain or hormone glands are damaged — it's more about how the system is working, not broken parts.
People with chronic fatigue or fibromyalgia often have a sluggish stress-response system and lower-than-normal cortisol levels, but not every study agrees because they look at different people or use different methods.
Your thyroid can still work normally even if you're not getting quite enough iodine, thanks to built-in backup systems that kick in for months or years.
People who don’t get quite enough iodine don’t seem to have a clear difference in thyroid problems compared to those who get enough — most studies show no big link, even though a few suggest there might be a small risk.
We don't have strong enough proof to say whether mild or moderate iodine deficiency really affects thyroid function, because the studies done so far aren't very reliable or consistent.
For kids, teens, and adults, not getting quite enough iodine doesn’t seem to clearly affect thyroid hormone levels — some studies see no change, others see mixed results, so we can’t say for sure either way.
Pregnant women with slightly low iodine levels don’t seem to have noticeable changes in their thyroid hormones compared to those with good iodine levels — their thyroid still works fine even if their iodine isn’t perfect.
Not getting enough iodine when kids are growing can hurt their brain development for good, because iodine is needed to make important brain hormones.
If jade perch on fish farms are fed homemade food that's really low in iodine and vitamin C, they might end up with thyroid problems — and this was seen in real farm conditions by checking the food and the fish's tissues.
Fish raised on farms might get thyroid tumors over time if their food lacks important nutrients, and we've seen signs of this in jade perch that were fed a poor diet.
Farmed jade perch are getting tumors in their thyroid because their food is missing important nutrients like iodine and vitamin C — scientists found this by checking the fish tissues and their feed.
When baby zebrafish have higher stress hormone levels early in life, it seems to change how certain genes in their brain work—turning down one gene linked to stress control and turning up another—hinting at how early stress might rewire their stress response system.