Browse evidence-based analysis of health-related claims and assertions
Log in to see full claim details, scientific mechanisms, and cited studies.
White adults with a certain gene variant have lower bad cholesterol and are nearly half as likely to get heart disease over 15 years — showing that even a small, lifelong drop in cholesterol can...
Black adults with a certain genetic mutation have much lower bad cholesterol and are way less likely to get heart disease over 15 years — this shows that keeping cholesterol low from an early age...
A specific part of the PCSK9 protein (the tail end) is needed to ship it out of liver cells; if this part is broken, less PCSK9 gets into the blood, so cholesterol stays lower.
Some cholesterol-lowering drugs called PCSK9 inhibitors can lower a specific type of blood fat linked to heart disease, and that might help protect people with high levels, but scientists aren't sure...
Blocking a protein called PCSK9 helps the immune system better recognize and attack cancer cells in mice, slowing tumor growth — and it works in a way that's not related to cholesterol.
A type of medicine (like evolocumab or alirocumab) blocks a protein in your body called PCSK9, which helps your liver remove bad cholesterol from your blood—cutting it by about half.
A protein called PCSK9 helps break down the liver's 'LDL cholesterol cleaners,' so more bad cholesterol stays in your blood, raising heart disease risk. People with certain PCSK9 gene changes either...
Genes have a bigger influence on how much people sit at work than on how much they sit during free time.
Just because someone sits a lot doesn’t mean they’re genetically wired to be less active — sitting and moving aren’t exact opposites in our DNA, even though they’re somewhat linked in behavior.
How much you say you sit and how much you actually sit are somewhat linked — about 1 in 3 people who report sitting a lot really do. And nearly half of that link comes from shared genes, meaning your...
People's genes seem to play a smaller role in how they report their sitting time compared to their actual sitting habits — meaning how much you say you sit isn't as influenced by DNA as how much you...
More than half of why people sit or recline different amounts every day comes down to their genes, not just their habits or surroundings.
IGF-1 helps build muscle by turning on growth signals inside cells, and the IGF-1 made in the muscle itself might matter more than the kind that comes from the liver.
Lifting weights makes your body release more growth hormone, especially when you do medium-heavy sets with short breaks. This effect is weaker in older people.
When women work out during the part of their cycle when estrogen is high, they might build more muscle because estrogen helps protect muscles and speed up recovery.
In young men, how sensitive their muscles are to testosterone—measured by androgen receptor levels—matters more for muscle growth than how much testosterone is in their blood.
When men lift weights, their testosterone helps their muscles grow by turning on certain signals in the muscle cells. This hormone response can last up to two days after a workout, making muscles...
Young men need normal testosterone levels to get the full muscle-building benefits from weight training — low testosterone blunts the body’s muscle-growth signals.
Young men with low testosterone don't get the same muscle-building boost from weight training because their bodies don't increase the machinery needed to make new proteins — and that seems to be...
When young men have low testosterone on purpose for the study, their muscles don’t respond as well to weight training at the cellular level — testosterone seems to help muscles fully 'feel' and react...
Young guys need their natural testosterone to get the full muscle-building benefits from weightlifting — if their testosterone is blocked with drugs, their muscles don’t grow as much, even if they...
If young guys are given a drug that lowers their testosterone, they don’t build much muscle from weight training—while others with normal testosterone gain about 1.5 kg of muscle in 6 weeks. This...
Rats that swam regularly didn't get blood sugar problems from stress like the ones that didn't exercise — their bodies handled sugar just as well as unstressed rats.
Stressing out male lab rats for a long time makes their bodies worse at handling sugar, even though their resting blood sugar stays the same.