Browse evidence-based analysis of health-related claims and assertions
A specific red light treatment made cartilage cells in a dish more active metabolically
A specific red light treatment made cartilage cells in a dish less active metabolically
A specific red light treatment made cartilage cells in a dish produce more of a protein that's typically associated with damaged or healing cartilage
A specific red light treatment made cartilage cells in a dish produce less of a protein that's typically associated with damaged or healing cartilage
A specific red light treatment made cartilage cells in a dish produce 40% more of a key structural protein that helps keep joints healthy
A specific red light treatment made cartilage cells in a dish produce more of a key structural protein that helps keep joints healthy
Shining a specific type of red light on cartilage cells in a dish made them produce more of the slippery substance that helps joints move smoothly
N-acetylcysteine supplementation at 300-600 mg/day provides optimal benefits for most individuals, with diminishing returns at higher doses and potential gastrointestinal side effects.
N-acetylcysteine supplementation reduces exercise-induced oxidative stress in skeletal muscle by serving as a glutathione precursor, thereby improving recovery and maintaining performance during repeated exercise bouts.
Hepatic glutathione depletion impairs fat metabolism and insulin signaling, leading to inefficient fat processing and blood sugar dysregulation; NAC supplementation restores hepatic glutathione levels, improving liver function and fat metabolism.
N-acetylcysteine suppresses TNF-alpha production in immune cells by approximately 56%, which mitigates obesity-induced insulin resistance by disrupting the inflammatory signaling pathway that impairs metabolic function.
N-acetylcysteine upregulates thermogenic genes (UCP3, PGC1α) in adipose tissue, increasing mitochondrial activity and energy expenditure, while reducing hyperinsulinemia and improving glucose clearance.
N-acetylcysteine increases glutathione availability in adipocytes, which reduces oxidative stress, decreases inflammatory signaling, and restores insulin sensitivity, thereby normalizing adipocyte function.
N-acetylcysteine reduces inflammatory markers (CD68, MCP-1) by over 80% and oxidative stress markers by approximately 70% in adipose tissue, while increasing adiponectin levels by nearly 90%, thereby improving insulin sensitivity.
In obesity, adipose tissue inflammation and oxidative stress impair insulin signaling, leading to reduced fat loss efficiency; NAC supplementation reduces inflammatory markers and oxidative stress in adipose tissue, improving metabolic function.
N-acetylcysteine serves as a precursor to glutathione, the body's primary intracellular antioxidant and detoxification molecule.
N-acetylcysteine (NAC) improves liver function, supports cellular detoxification, modulates inflammation in adipose tissue, enhances fat loss, and improves recovery from physical exertion.
This study doesn't show that selenium or N-acetyl-cysteine helps men with infertility from other causes have better sperm quality or fertility.
This study doesn't show that selenium or N-acetyl-cysteine helps men without specific infertility issues have better sperm quality or fertility.
Taking selenium or N-acetyl-cysteine for 6 months doesn't have enough data to know if it's safe long-term for men with certain types of infertility.
The benefits of selenium and N-acetyl-cysteine on sperm quality for men with certain types of infertility only last while they're taking the supplements, and may go away after stopping.