Browse evidence-based analysis of health-related claims and assertions
When mice don't get enough potassium, their kidney transporter becomes more active and blood pressure rises, but a common blood pressure drug can lower it again.
Correlational
Mice have the lowest blood pressure when their blood potassium is around 4.5 mM, but higher or lower levels raise blood pressure.
Even though high potassium lowers a kidney transporter in mice, this doesn't explain the blood pressure changes, suggesting other mechanisms are at play.
Long-term high potassium makes a kidney channel more active, and blocking that channel with a drug lowers blood pressure in mice.
For a few days, extra potassium lowers mice's blood pressure, but after three weeks, it starts to raise it again.
When mice eat a lot of potassium for three weeks, their blood pressure goes up mostly at night, no matter how much salt they eat or what form of potassium they consume.
Adults with type 2 diabetes who practiced yoga had about 0.5 lower BMI scores than those who didn't exercise, after 12 weeks.
Adults with type 2 diabetes who did aerobic exercise had about 0.6 lower BMI scores than those who didn't exercise, after 12 weeks.
Adults with type 2 diabetes who practiced yoga had about 17 less ng/mL of ICAM-1 (an inflammation marker) than those who didn't exercise, after 12 weeks.
Adults with type 2 diabetes who did aerobic exercise had about 27 less ng/mL of ICAM-1 (an inflammation marker) than those who didn't exercise, after 12 weeks.
Adults with type 2 diabetes who practiced yoga had about 0.6 lower insulin resistance scores than those who didn't exercise, after 12 weeks.
Adults with type 2 diabetes who did aerobic exercise had about 0.6 lower insulin resistance scores than those who didn't exercise, after 12 weeks.
Adults with type 2 diabetes who practiced yoga had about 13 more mg/dL lower fasting blood sugar than those who didn't exercise, after 12 weeks.
Adults with type 2 diabetes who did aerobic exercise had about 12 more mg/dL lower fasting blood sugar than those who didn't exercise, after 12 weeks.
Adults with type 2 diabetes who practiced yoga lost about 1.2 more kilograms than those who didn't exercise, after 12 weeks.
Adults with type 2 diabetes who did aerobic exercise lost about 1.5 more kilograms than those who didn't exercise, after 12 weeks.
In blood vessel cells under high sugar conditions, uric acid makes them produce more inflammation markers, but insulin doesn't have this effect.
Causal
When immune cells called monocytes are exposed to a bacterial toxin, adding uric acid and insulin together makes them produce more inflammation-related molecules than the toxin alone.
People with type 2 diabetes who take SGLT-2 inhibitors tend to have lower fasting insulin levels than those using other diabetes drugs.
Type 2 diabetes patients taking SGLT-2 inhibitors have lower levels of uric acid in their blood than those on other diabetes medications.
People with type 2 diabetes who take SGLT-2 inhibitors tend to have lower levels of a key inflammation marker called interleukin-6 than those taking other diabetes medications.
In Korean adults with healthy kidneys, the link between insulin resistance and kidney disease risk doesn't change based on age, gender, high blood pressure, or obesity status.
Korean adults with healthy kidneys who have higher leptin-to-adiponectin ratios (a marker of metabolic dysfunction) are 23% more likely to develop kidney disease over 11 years.
Korean adults with healthy kidneys who have lower QUICKI scores (indicating worse insulin sensitivity) have a 38% higher chance of developing kidney disease over 11 years compared to those with higher QUICKI scores.