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Average study score: 4/100
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1 study attributed to Benita S. Katzenellenbogen on the platform. Click a card to read the full analysis.
Study
Ligand-dependent, transcriptionally productive association of the amino- and carboxyl-terminal regions of a steroid hormone nuclear receptor.
To test whether the amino-terminal activation function (AF-1) and carboxyl-terminal ligand-binding activation function (AF-2) of the estrogen receptor (ER) can functionally interact when expressed as separate polypeptides in mammalian cells, and to determine the role of ligand binding in that interaction.