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    Posts/Bluesky/@robertlufkinmd.bsky.social
    Robert Lufkin MD

    Robert Lufkin MD

    @robertlufkinmd.bsky.social

    Bluesky
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    Bluesky
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    Robert Lufkin MD
    Robert Lufkin MD@robertlufkinmd.bsky.social

    Honest caveat: this is a mouse study. The mechanism is elegant, but no human trial has shown that a 15-PGDH inhibitor protects muscle in people on GLP-1s. Lifestyle is still the foundation: resistance training plus ~1.6 g/kg of protein remains the proven way to keep muscle on these drugs. (4/6)

    Disagreement
    11 supports3 challenges
    Jul 2, 2026View analysis

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