@robertlufkinmd.bsky.social
Every post by Robert Lufkin MD we've fact-checked.
Honest caveat: this is a mouse study. The mechanism is elegant, but no human trial has shown that a 15-PGDH inhibitor protects muscle in people on GLP-1s. Lifestyle is still the foundation: resistance training plus ~1.6 g/kg of protein remains the proven way to keep muscle on these drugs. (4/6)