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The Study

Longitudinal Performance Changes in Transgender Women Athletes Pre and Post Gender Affirming Hormone Therapy

In simple terms

This study watches a small group of transgender women athletes over time to see how their race times and training change after starting hormone therapy. It can show patterns or links, like 'when training went up, performance stayed better,' but it can't prove that the hormones caused the changes because many other things could have affected the results.

44%

Analysis score

44/ 72

Maximum 72 for a cohort study.

Where the score came from

Reporting0
Methodology14
Publication100
Statistical77
Study type (basis of the score)
Cohort Study
Level 2b - Individual cohort study
What’s the bottom line?

This study looked at how hormone therapy changes how fast transgender women run and swim by comparing their race times before and after treatment.

Where does this study sit?

Reviews of RCTs (Meta-analyses)

Max 100

Randomized Trials

Max 90

Reviews of Cohort Studies

Max 85

Cohort Studies

Max 72

Reviews of Case-Control Studies

Max 63

Case-Control Studies

Max 58

Cross-Sectional & Case Series

Max 50

Expert Opinion

Max 5
StrongerWeaker
Cohort Studies
Level 2b
44

44 / 100

Quality score

Groups of people are followed over time to see who develops an outcome. Strong for identifying risk factors and associations, but cannot prove causation as firmly as RCTs.

Cannot establish causation

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Key takeaways

Summary

Based on the study abstract and findings.

  1. 1Yes, the results are meaningful: hormone therapy reduces athletic performance, especially in endurance events, but training can help reduce the loss.
  2. 2The athletes remain similarly competitive in the women’s category.
  3. 3After hormone therapy, runners were about 15% slower on average.
  4. 4Long races slowed more than short ones.
  5. 5One swimmer was 5% slower.
  6. 6Testosterone dropped to typical female levels.
  7. 7Even though times got slower, they stayed just as competitive in their age group.

Score breakdown, methodology, conflicts of interest, evidence analysis & raw study data

Publication

Journal

European Journal of Sport Science

Year

2025

Authors

Joanna Harper, R. Blagrove, E. Hunsicker, G. Witcomb, R. Ferguson, E. O’Donnell

Open Access
1 citations
Analysis v5
Fit Body Science verdict — we translate health studies into clear verdicts backed by peer-reviewed research.

Not medical advice. For informational purposes only. Always consult a qualified healthcare professional before making health decisions.