Does a cholesterol drug help prevent heart problems in people who haven't had a heart attack or stroke?
Rationale and Design of the Effect of EVolocumab in PatiEntS at High CArdiovascuLar RIsk WithoUt Prior Myocardial Infarction or Stroke (VESALIUS-CV) Trial.
Not medical advice. For informational purposes only. Always consult a healthcare professional. Terms
Doctors are testing a drug called evolocumab to see if it helps prevent heart attacks, strokes, and other heart problems in people at high risk but who haven't had one yet.
No biological mechanisms were identified in this study. This may be an epidemiological, observational, or survey-based study that reports associations rather than proposing causal biological pathways.
Systematic Reviews & Meta-Analyses
Max 100Randomized Controlled Trials
Max 90Cohort Studies
Max 72Case-Control Studies
Max 58Cross-Sectional Studies
Max 44Case Reports & Case Series
Max 30Expert Opinion & Narrative Reviews
Max 555 / 90
Evidence Score
Participants are randomly assigned to treatment or control groups, minimizing bias. Considered the gold standard for testing whether an intervention causes an effect.
Not medical advice. For informational purposes only. Always consult a healthcare professional. Terms
Doctors are testing a drug called evolocumab to see if it helps prevent heart attacks, strokes, and other heart problems in people at high risk but who haven't had one yet.
No biological mechanisms were identified in this study. This may be an epidemiological, observational, or survey-based study that reports associations rather than proposing causal biological pathways.
Systematic Reviews & Meta-Analyses
Max 100Randomized Controlled Trials
Max 90Cohort Studies
Max 72Case-Control Studies
Max 58Cross-Sectional Studies
Max 44Case Reports & Case Series
Max 30Expert Opinion & Narrative Reviews
Max 555 / 90
Evidence Score
Participants are randomly assigned to treatment or control groups, minimizing bias. Considered the gold standard for testing whether an intervention causes an effect.
Publication
Authors
Bohula EA, Marston NA, Ruzza A, Murphy SA, De Ferrari GM, Diaz R, Leiter LA, Elliott-Davey M, Wang H, Bhatia AK, Giugliano RP, Sabatine MS
Related Content
Claims (4)
Taking a drug called evolocumab can lower the chance of having a first major heart problem by 25% in people at high risk who’ve never had a heart attack or stroke before.
A big heart study is checking if adding a drug called evolocumab to usual cholesterol treatment helps prevent heart attacks, strokes, or heart-related deaths in people at high risk who haven’t had one before.
They're testing if a drug called Evolocumab, given as a shot every two weeks, can help prevent serious heart problems in people with artery disease or high-risk diabetes who haven't had a heart attack or stroke yet.
Does the drug evolocumab help prevent heart attacks, strokes, or related heart problems in people with artery disease or high-risk diabetes who haven't had a heart attack or stroke before?