Can a special wheat bran compound help heal a sick gut?
Enzymatically Hydrolyzed Wheat Bran-Derived Zinc Phytate Ameliorates Ulcerative Colitis via Synergistic Regulation of the Gut Microbiota-Intestinal Barrier Axis.
Not medical advice. For informational purposes only. Always consult a healthcare professional. Terms
Scientists gave mice with inflamed guts a special form of zinc from wheat bran and saw their gut bacteria and healing proteins improve.
Systematic Reviews & Meta-Analyses
Max 100Randomized Controlled Trials
Max 90Cohort Studies
Max 72Case-Control Studies
Max 58Cross-Sectional Studies
Max 44Case Reports & Case Series
Max 30Expert Opinion & Narrative Reviews
Max 58 / 72
Evidence Score
Groups of people are followed over time to see who develops an outcome. Strong for identifying risk factors and associations, but cannot prove causation as firmly as RCTs.
Not medical advice. For informational purposes only. Always consult a healthcare professional. Terms
Scientists gave mice with inflamed guts a special form of zinc from wheat bran and saw their gut bacteria and healing proteins improve.
Systematic Reviews & Meta-Analyses
Max 100Randomized Controlled Trials
Max 90Cohort Studies
Max 72Case-Control Studies
Max 58Cross-Sectional Studies
Max 44Case Reports & Case Series
Max 30Expert Opinion & Narrative Reviews
Max 58 / 72
Evidence Score
Groups of people are followed over time to see who develops an outcome. Strong for identifying risk factors and associations, but cannot prove causation as firmly as RCTs.
Publication
Authors
Zhang L, Zhan M, Zhao Y, Wang B, Lin D, Ren D, Yang X, Zhao A
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Claims (7)
Phytic acid, a compound found in plants, plays a role in biological processes that support the function and condition of the gastrointestinal tract.
Phytic acid, a compound found in certain plant foods, is associated with improved function of the intestinal lining and reduced levels of inflammation-related molecules in the gut.
A modified form of zinc from wheat bran may help treat ulcerative colitis by changing gut bacteria, bile acids, and the proteins that line the intestine, based on tests in mice.
The bacterium Lactobacillus vaginalis can break down zinc bound to phytate in wheat bran, releasing zinc and specific inositol phosphate compounds that may be more easily absorbed by the body.
A modified form of zinc from wheat bran increases the production of proteins that strengthen the gut lining and reduces activity in a signaling pathway linked to inflammation in mice with induced intestinal inflammation.