A shot that helps people with heavy knees feel better
Once-Weekly Semaglutide in Persons with Obesity and Knee Osteoarthritis.
Not medical advice. For informational purposes only. Always consult a healthcare professional. Terms
Some people who weigh a lot and have bad knee pain got a weekly shot for over a year. One group got a medicine called semaglutide, and the other got a fake shot. Everyone also got advice on moving more and eating less.
Practical Takeaways
For adults with obesity and knee osteoarthritis, discussing GLP-1 agonists like semaglutide with a doctor may help both weight and joint symptoms.
Not medical advice. For informational purposes only. Always consult a healthcare professional. Terms
Some people who weigh a lot and have bad knee pain got a weekly shot for over a year. One group got a medicine called semaglutide, and the other got a fake shot. Everyone also got advice on moving more and eating less.
Practical Takeaways
For adults with obesity and knee osteoarthritis, discussing GLP-1 agonists like semaglutide with a doctor may help both weight and joint symptoms.
Publication
Journal
The New England journal of medicine
Year
2024
Authors
H. Bliddal, Harold E. Bays, S. Czernichow, Joanna Uddén Hemmingsson, J. Hjelmesæth, Thomas Hoffmann Morville, Anna Koroleva, Jesper Skov Neergaard, Patricia Vélez Sánchez, Sean Wharton, Alicja Wizert, L. E. Kristensen
Related Content
Claims (3)
A weekly semaglutide shot helped people with obesity and knee pain from arthritis feel a lot better—much more than those who got a dummy shot.
People with obesity and knee arthritis who took a weekly semaglutide shot for over a year felt physically better than those who took a dummy shot — their ability to do everyday physical activities improved more, by about twice as much.
A weekly shot called semaglutide helped people with obesity and bad knee arthritis lose way more weight—about 13.7% of their body weight—compared to a fake shot that only led to 3.2% loss, and that weight loss might help their joint pain feel better.