The Study
Effects of 8-weeks of supplementation with a plant protein blend + creatine monohydrate on changes in maximal strength in resistance-trained males and females
This study tested if different protein drinks plus creatine help people get stronger. Everyone got stronger, but none of the drinks were clearly better than the others. So we know taking something helps, but we can't say which one is the best.
Analysis score
Maximum 90 for a randomized controlled trial.
Where the score came from
People who lifted weights 4 days a week for 8 weeks got stronger no matter what they drank—plant protein, whey, creatine, or just sugar water.
Where does this study sit?
Reviews of RCTs (Meta-analyses)
Max 100Randomized Trials
Max 90Reviews of Cohort Studies
Max 85Cohort Studies
Max 72Reviews of Case-Control Studies
Max 63Case-Control Studies
Max 58Cross-Sectional & Case Series
Max 50Expert Opinion
Max 554 / 100
Quality score
Participants are randomly assigned to treatment or control groups, minimizing bias. The gold standard for testing whether an intervention causes an effect.
Key takeaways
Summary
Based on the study abstract and findings.
- 1Yes—training itself was the main driver of gains; supplements didn’t add extra benefit.
- 2Everyone got 7–12% stronger on deadlifts and bench presses, and did 14–27% more reps.
- 3No group did better than another.
Score breakdown, methodology, conflicts of interest, evidence analysis & raw study data
Publication
Journal
Journal of the International Society of Sports Nutrition
Year
2025
Authors
A. Hagele, Kevin F. Holley, Alex C. Schrautemeier, James L. Tice, Joshua M. Iannotti, J. Krieger, C. Gaige, Wyatt B. McLaughlin, Ralf Jäger, C. Kerksick
Related Content
Claims (5)
Among adults who regularly lift weights, taking a plant-based protein supplement with creatine for 8 weeks leads to the same changes in maximum strength and exercise capacity as taking whey protein or a carbohydrate placebo.
In resistance-trained adults, taking creatine monohydrate with plant protein does not lead to greater increases in maximal strength or work capacity than taking plant protein alone over eight weeks.
Adults who regularly lift weights and take protein or carbohydrate supplements for eight weeks, training four days per week, show increased maximal strength and work capacity, and these improvements are due to the training program.
Resistance-trained adults who take 48 grams of plant-based protein daily with or without 5 grams of creatine monohydrate for 8 weeks while following a 4-day-per-week resistance training program experience increases in maximal strength by 7.2–12.2% and in work capacity by 14.1–26.9%, regardless of whether the supplement is plant protein, whey protein, or a carbohydrate placebo.
In people who train with weights, taking plant protein with creatine leads to the same increases in strength and workout performance as taking whey protein.
Not medical advice. For informational purposes only. Always consult a qualified healthcare professional before making health decisions.