Does a hormone rush make your arms bigger?

Original Title

Elevations in ostensibly anabolic hormones with resistance exercise enhance neither training-induced muscle hypertrophy nor strength of the elbow flexors.

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Summary

Two guys trained their arms the same way, but one got a big hormone boost from doing leg exercises right after. The other didn't. Both got equally strong and their arms grew the same amount.

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Surprising Findings

Massive hormone spikes (testosterone, GH, IGF-1) had zero effect on muscle growth or strength gains—even though they were statistically significant (p < 0.001).

For decades, fitness gurus and even textbooks claimed that post-workout hormone surges were essential for hypertrophy. This study directly contradicts that with controlled, within-subject data.

Practical Takeaways

Skip the leg-day-before-arm-day routine. Focus on progressive overload, full range of motion, and sufficient volume for your target muscles—no need to chase hormonal surges.

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45%
Moderate QualityOverall Score

Publication

Journal

Journal of applied physiology

Year

2010

Authors

Daniel W D West, N. Burd, Jason E. Tang, D. Moore, Aaron W. Staples, A. Holwerda, S. Baker, Stuart M Phillips

Open Access
299 citations
Analysis v1
Does a hormone rush make your arms bigger? — Quality Score & Summary | Fit Body Science