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How a plant chemical stops sticky cells from starting artery clogs

Original Title

Selective inhibition of tumor necrosis factor-induced vascular cell adhesion molecule-1 gene expression by a novel flavonoid. Lack of effect on transcription factor NF-kappa B.

doi:10.1161/01.ATV.16.12.1501
4%

Lower Quality

Methodology score · 4/100

Cross Sectional In Vitro
Fit Body Science breakdown

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What’s the bottom line?

A plant chemical called PD 098063 stops a specific sticky protein (VCAM-1) from appearing on blood vessel cells when they're irritated, without affecting other similar proteins.

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Publication

Authors

Wölle J, Hill RR, Ferguson E, Devall LJ, Trivedi BK, Newton RS, Saxena U