Does a diabetes shot help keep people out of the hospital?
Effect of Once-Weekly Exenatide in Patients With Type 2 Diabetes With and Without Heart Failure and Heart Failure-Related Outcomes: Insights From the EXSCEL Trial.
Not medical advice. For informational purposes only. Always consult a healthcare professional. Terms
Surprising Findings
The drug cuts repeat heart failure hospitalizations but not the first one.
Most treatments aim to prevent the first major event. Here, exenatide failed to stop the initial hospitalization but significantly reduced repeat visits—a rare and counterintuitive pattern.
Practical Takeaways
If you have type 2 diabetes and a healthy heart, ask your doctor if a GLP-1 RA like exenatide could help lower your risk of death.
Not medical advice. For informational purposes only. Always consult a healthcare professional. Terms
Surprising Findings
The drug cuts repeat heart failure hospitalizations but not the first one.
Most treatments aim to prevent the first major event. Here, exenatide failed to stop the initial hospitalization but significantly reduced repeat visits—a rare and counterintuitive pattern.
Practical Takeaways
If you have type 2 diabetes and a healthy heart, ask your doctor if a GLP-1 RA like exenatide could help lower your risk of death.
Publication
Journal
Circulation
Year
2019
Authors
M. Fudim, Jennifer A. White, N. Pagidipati, Y. Lokhnygina, J. Wainstein, J. Murín, N. Iqbal, P. Öhman, R. Lopes, B. Reicher, R. Holman, Adrian F. Hernandez, R. Mentz
Related Content
Claims (6)
Taking a weekly diabetes shot called exenatide may help lower the chance of dying or ending up in the hospital with heart failure for people with type 2 diabetes.
If you have type 2 diabetes and already have heart failure, the weekly diabetes shot exenatide might not help you live longer or keep you out of the hospital for heart problems. But if your heart is healthy, it could lower your risk of dying by 21%.
A weekly diabetes shot called exenatide doesn’t lower the chance of ending up in the hospital for heart failure for the first time in people with type 2 diabetes — it’s basically neutral, even though it might help if someone already has heart issues.
A diabetes drug made from Gila monster spit doesn't just help blood sugar — it can also help people lose weight, protect the heart, and even reduce cravings for things like alcohol or drugs.
A weekly diabetes shot called exenatide may help people with type 2 diabetes live longer, especially if they don’t already have heart failure.