Does a diabetes shot help keep people out of the hospital?
Effect of Once-Weekly Exenatide in Patients With Type 2 Diabetes With and Without Heart Failure and Heart Failure-Related Outcomes: Insights From the EXSCEL Trial.
Not medical advice. For informational purposes only. Always consult a healthcare professional. Terms
A special weekly shot for diabetes called exenatide helps some people live longer and avoid repeat heart failure hospital stays—but only if they don’t already have heart failure.
No biological mechanisms were identified in this study. This may be an epidemiological, observational, or survey-based study that reports associations rather than proposing causal biological pathways.
Systematic Reviews & Meta-Analyses
Max 100Randomized Controlled Trials
Max 90Cohort Studies
Max 72Case-Control Studies
Max 58Cross-Sectional Studies
Max 44Case Reports & Case Series
Max 30Expert Opinion & Narrative Reviews
Max 590 / 90
Evidence Score
Participants are randomly assigned to treatment or control groups, minimizing bias. Considered the gold standard for testing whether an intervention causes an effect.
Not medical advice. For informational purposes only. Always consult a healthcare professional. Terms
A special weekly shot for diabetes called exenatide helps some people live longer and avoid repeat heart failure hospital stays—but only if they don’t already have heart failure.
No biological mechanisms were identified in this study. This may be an epidemiological, observational, or survey-based study that reports associations rather than proposing causal biological pathways.
Systematic Reviews & Meta-Analyses
Max 100Randomized Controlled Trials
Max 90Cohort Studies
Max 72Case-Control Studies
Max 58Cross-Sectional Studies
Max 44Case Reports & Case Series
Max 30Expert Opinion & Narrative Reviews
Max 590 / 90
Evidence Score
Participants are randomly assigned to treatment or control groups, minimizing bias. Considered the gold standard for testing whether an intervention causes an effect.
Publication
Authors
Fudim M, White J, Pagidipati NJ, Lokhnygina Y, Wainstein J, Murin J, Iqbal N, Öhman P, Lopes RD, Reicher B, Holman RR, Hernandez AF, Mentz RJ
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Claims (6)
Taking a weekly diabetes shot called exenatide may help lower the chance of dying or ending up in the hospital with heart failure for people with type 2 diabetes.
If you have type 2 diabetes and already have heart failure, the weekly diabetes shot exenatide might not help you live longer or keep you out of the hospital for heart problems. But if your heart is healthy, it could lower your risk of dying by 21%.
A weekly diabetes shot called exenatide doesn’t lower the chance of ending up in the hospital for heart failure for the first time in people with type 2 diabetes — it’s basically neutral, even though it might help if someone already has heart issues.
A weekly diabetes shot called exenatide may help people with type 2 diabetes live longer, especially if they don’t already have heart failure.
Taking a weekly diabetes shot called exenatide doesn’t stop the first heart failure hospital stay, but it does cut down on how often people end up back in the hospital for heart problems by about 18%.