The Study
Consumption of Whole Grain and Legume Powder Reduces Insulin Demand, Lipid Peroxidation, and Plasma Homocysteine Concentrations in Patients With Coronary Artery Disease: Randomized Controlled Clinical Trial
This study is like a fair test where one group ate a special powder instead of white rice, and the other kept eating white rice. The group with the powder had better blood numbers, but we can't say for sure the powder caused it because we don't know if everyone was blind to which group they were in. So we can say it probably helped, but we can't say it definitely caused the changes.
Analysis score
Maximum 90 for a randomized controlled trial.
Where the score came from
People with heart disease ate a special powder made from whole grains and beans instead of white rice for 16 weeks, and their blood sugar and stress markers got much better.
Where does this study sit?
Reviews of RCTs (Meta-analyses)
Max 100Randomized Trials
Max 90Reviews of Cohort Studies
Max 85Cohort Studies
Max 72Reviews of Case-Control Studies
Max 63Case-Control Studies
Max 58Cross-Sectional & Case Series
Max 50Expert Opinion
Max 556 / 100
Quality score
Participants are randomly assigned to treatment or control groups, minimizing bias. The gold standard for testing whether an intervention causes an effect.
Key takeaways
Summary
Based on the study abstract and findings.
- 1Yes — these changes mean less strain on the body’s sugar system, less damage from free radicals, and lower risk for heart attacks and diabetes.
- 2Blood sugar dropped 24%, insulin dropped 14%, oxidative stress markers fell 28%, homocysteine dropped 32%, and key antioxidants like vitamin E and carotene rose 11–40%.
Score breakdown, methodology, conflicts of interest, evidence analysis & raw study data
Publication
Journal
Arteriosclerosis, Thrombosis, and Vascular Biology: Journal of the American Heart Association
Year
2001
Authors
Y. Jang, J. H. Lee, O. Y. Kim, H. Park, Sang Yun Lee
Related Content
Claims (6)
Eating legumes leads to better blood sugar regulation and improved gut health due to their fiber and resistant starch content.
In men with coronary artery disease, replacing refined rice with whole grain and legume powder for 16 weeks lowers levels of two biomarkers of oxidative stress in the blood and urine by about 28%.
In men with coronary artery disease, substituting refined rice with whole grain and legume powder for 16 weeks lowers plasma homocysteine levels by about 32%, regardless of folate level changes.
In men with coronary artery disease, replacing refined rice with an equal amount of whole grain and legume powder daily for 16 weeks lowers fasting blood glucose by 24% and fasting insulin by 14%, improves insulin sensitivity, and reduces the total glucose and insulin response during a sugar tolerance test.
In men with coronary artery disease, substituting refined rice with whole grain and legume powder for 16 weeks raises the level of n-6 fatty acids in blood cell membranes by 14%, which changes the physical properties of the membranes and affects inflammatory signaling molecules.
In men with coronary artery disease, replacing refined rice with whole grain and legume powder for 16 weeks raises blood levels of α-carotene, retinol, and α-tocopherol by 11% to 40%, reflecting higher antioxidant levels and better nutrient retention or less oxidative loss.
Not medical advice. For informational purposes only. Always consult a qualified healthcare professional before making health decisions.