Why your muscles switch from fat to sugar after eating
Suppression of systemic, intramuscular, and subcutaneous adipose tissue lipolysis by insulin in humans.
Not medical advice. For informational purposes only. Always consult a healthcare professional. Terms
After you eat, insulin tells your body to stop breaking down fat. This study found that muscle stops fat breakdown more easily than fat tissue, even though muscle still breaks down a bit more fat under high insulin.
Systematic Reviews & Meta-Analyses
Max 100Randomized Controlled Trials
Max 90Cohort Studies
Max 72Case-Control Studies
Max 58Cross-Sectional Studies
Max 44Case Reports & Case Series
Max 30Expert Opinion & Narrative Reviews
Max 541 / 90
Evidence Score
Participants are randomly assigned to treatment or control groups, minimizing bias. Considered the gold standard for testing whether an intervention causes an effect.
Not medical advice. For informational purposes only. Always consult a healthcare professional. Terms
After you eat, insulin tells your body to stop breaking down fat. This study found that muscle stops fat breakdown more easily than fat tissue, even though muscle still breaks down a bit more fat under high insulin.
Systematic Reviews & Meta-Analyses
Max 100Randomized Controlled Trials
Max 90Cohort Studies
Max 72Case-Control Studies
Max 58Cross-Sectional Studies
Max 44Case Reports & Case Series
Max 30Expert Opinion & Narrative Reviews
Max 541 / 90
Evidence Score
Participants are randomly assigned to treatment or control groups, minimizing bias. Considered the gold standard for testing whether an intervention causes an effect.
Publication
Journal
The Journal of clinical endocrinology and metabolism
Year
2000
Authors
M. Stumvoll, S. Jacob, H. Wahl, B. Hauer, K. Löblein, P. Grauer, R. Becker, M. Nielsen, W. Renn, Hans U. Häring
Related Content
Claims (4)
When insulin levels rise, it reduces the breakdown of fat in fat cells by suppressing the enzyme hormone-sensitive lipase.
When insulin levels are maximally elevated, fat breakdown is more strongly suppressed in fat tissue than in muscle tissue, meaning muscle continues to break down more fat even under strong insulin signaling.
In people, the amount of insulin needed to suppress fat breakdown is related to how well their body uses insulin to absorb glucose. Those who are more sensitive to insulin for glucose uptake also tend to require less insulin to stop fat breakdown.
In healthy, lean individuals, insulin reduces the breakdown of fat in both fat tissue and muscle, and muscle tissue requires less insulin to achieve this effect than fat tissue.