Can selenium pills help reduce eye swelling in thyroid disease?

Original Title

6662 Effect of Selenium Supplementation on Mild Graves’ Ophthalmopathy at a Tertiary Hospital - A Six-Month Open-Labelled, Assessor-Masked, Randomized-Controlled Trial

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Summary

People with mild eye swelling from an overactive thyroid were given either selenium pills or just eye drops for six months to see which helped more.

Proposed Mechanism
Selenium-mediated reduction of oxidative stress and inflammation in Graves' ophthalmopathy
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Quality Analysis
Methodology
53%
Moderate QualityOverall Score
Randomized Controlled TrialMedicine

Systematic Reviews & Meta-Analyses

Max 100

Randomized Controlled Trials

Max 90

Cohort Studies

Max 72

Case-Control Studies

Max 58

Cross-Sectional Studies

Max 44

Case Reports & Case Series

Max 30

Expert Opinion & Narrative Reviews

Max 5
StrongerWeaker
Randomized Controlled Trials
Level 1b
53

53 / 90

Evidence Score

Participants are randomly assigned to treatment or control groups, minimizing bias. Considered the gold standard for testing whether an intervention causes an effect.

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