A new shot that helps people lose lots of weight and control sugar in their blood
Retatrutide (LY3437943) for metabolic disorders: A systematic review of clinical outcomes in obesity and type 2 diabetes
Not medical advice. For informational purposes only. Always consult a healthcare professional. Terms
Surprising Findings
Over half of type 2 diabetes patients lost 15% or more of their body weight — something previously seen only with bariatric surgery.
Until now, only gastric bypass reliably achieved 15%+ weight loss. Drugs like Ozempic average 10–12%. Retatrutide may close the gap between surgery and medication.
Practical Takeaways
Talk to your doctor about emerging weight loss and diabetes drugs if you haven’t reached your health goals with current treatments.
Not medical advice. For informational purposes only. Always consult a healthcare professional. Terms
Surprising Findings
Over half of type 2 diabetes patients lost 15% or more of their body weight — something previously seen only with bariatric surgery.
Until now, only gastric bypass reliably achieved 15%+ weight loss. Drugs like Ozempic average 10–12%. Retatrutide may close the gap between surgery and medication.
Practical Takeaways
Talk to your doctor about emerging weight loss and diabetes drugs if you haven’t reached your health goals with current treatments.
Publication
Journal
Indian Journal of Physiology and Pharmacology
Year
2026
Authors
Shruti Singh, Rajesh Kumar, V. Maharshi, Nishita Sinha, Shuvasree Payra
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Claims (5)
A shot called retatrutide, given once a week, helped people with obesity lose nearly a quarter of their body weight over a year—some losing around 57 pounds—much more than those on a dummy shot.
A drug called retatrutide, taken once a week, helped lower blood sugar a lot in people with type 2 diabetes over 9 months — more than a placebo or another diabetes drug.
Taking a drug called retatrutide can shrink your waist by nearly 8 inches over a year if you're an adult with obesity, which means you're losing dangerous belly fat that's linked to heart and metabolic problems.
Retatrutide, a diabetes drug, helped nearly 6 out of 10 adults lose at least 15% of their body weight in less than a year — way more than another drug called dulaglutide, which only helped 2 out of 10 people hit that goal.
Retatrutide keeps helping people lose weight steadily for a whole year without slowing down, while other weight-loss drugs like GLP-1s tend to stop working as well after a few months.