A new shot that helps people lose lots of weight and control sugar in their blood
Retatrutide (LY3437943) for metabolic disorders: A systematic review of clinical outcomes in obesity and type 2 diabetes
Not medical advice. For informational purposes only. Always consult a healthcare professional. Terms
A medicine called retatrutide helps people with obesity or type 2 diabetes lose weight and lower their blood sugar. It works better than older medicines, especially at higher doses.
No biological mechanisms were identified in this study. This may be an epidemiological, observational, or survey-based study that reports associations rather than proposing causal biological pathways.
Systematic Reviews & Meta-Analyses
Max 100Randomized Controlled Trials
Max 90Cohort Studies
Max 72Case-Control Studies
Max 58Cross-Sectional Studies
Max 44Case Reports & Case Series
Max 30Expert Opinion & Narrative Reviews
Max 520 / 100
Evidence Score
The highest quality evidence. These studies systematically search, appraise, and synthesize results from multiple individual studies, providing the most reliable summary of current knowledge.
Not medical advice. For informational purposes only. Always consult a healthcare professional. Terms
A medicine called retatrutide helps people with obesity or type 2 diabetes lose weight and lower their blood sugar. It works better than older medicines, especially at higher doses.
No biological mechanisms were identified in this study. This may be an epidemiological, observational, or survey-based study that reports associations rather than proposing causal biological pathways.
Systematic Reviews & Meta-Analyses
Max 100Randomized Controlled Trials
Max 90Cohort Studies
Max 72Case-Control Studies
Max 58Cross-Sectional Studies
Max 44Case Reports & Case Series
Max 30Expert Opinion & Narrative Reviews
Max 520 / 100
Evidence Score
The highest quality evidence. These studies systematically search, appraise, and synthesize results from multiple individual studies, providing the most reliable summary of current knowledge.
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Claims (5)
A shot called retatrutide, given once a week, helped people with obesity lose nearly a quarter of their body weight over a year—some losing around 57 pounds—much more than those on a dummy shot.
A drug called retatrutide, taken once a week, helped lower blood sugar a lot in people with type 2 diabetes over 9 months — more than a placebo or another diabetes drug.
Taking a drug called retatrutide can shrink your waist by nearly 8 inches over a year if you're an adult with obesity, which means you're losing dangerous belly fat that's linked to heart and metabolic problems.
Retatrutide, a diabetes drug, helped nearly 6 out of 10 adults lose at least 15% of their body weight in less than a year — way more than another drug called dulaglutide, which only helped 2 out of 10 people hit that goal.
Retatrutide keeps helping people lose weight steadily for a whole year without slowing down, while other weight-loss drugs like GLP-1s tend to stop working as well after a few months.