A shot called retatrutide, given once a week, helped people with obesity lose nearly a quarter of their body weight over a year—some losing around 57 pounds—much more than those on a dummy shot.

People with obesity who took a shot called retatrutide once a week for a year lost nearly a quarter of their body weight—way more than those who got a dummy shot. This makes it one of the strongest weight-loss medicines we’ve seen so far.

Most people with obesity who take a high dose of a drug called retatrutide every week for nearly a year lose at least 15% of their body weight — that’s like dropping 30 pounds if you weigh 200. Almost no one on a fake pill loses that much.

People who get a weekly shot of a new medicine called retatrutide are about 18 times more likely to lose at least 15% of their body weight than those who get a placebo, which could mean a lot of them reach a weight loss level that really improves their health.

Adults with obesity or type 2 diabetes who take a weekly 12 mg dose of retatrutide are way more likely—over 70 times more—to lose at least 15% of their body weight in less than a year compared to those taking a fake pill.

Retatrutide, a diabetes drug, helped nearly 6 out of 10 adults lose at least 15% of their body weight in less than a year — way more than another drug called dulaglutide, which only helped 2 out of 10 people hit that goal.