Which way works better to fix baby’s vitamin D: pill or shot?
Comparison of the Effect of Oral Versus Parenteral Vitamin D on Serum Levels of Vitamin D in Premature Infants with Vitamin D Deficiency
Not medical advice. For informational purposes only. Always consult a healthcare professional. Terms
Doctors gave tiny premature babies either a daily vitamin D pill or one big shot to fix their low vitamin D levels.
Systematic Reviews & Meta-Analyses
Max 100Randomized Controlled Trials
Max 90Cohort Studies
Max 72Case-Control Studies
Max 58Cross-Sectional Studies
Max 44Case Reports & Case Series
Max 30Expert Opinion & Narrative Reviews
Max 554 / 90
Evidence Score
Participants are randomly assigned to treatment or control groups, minimizing bias. Considered the gold standard for testing whether an intervention causes an effect.
Not medical advice. For informational purposes only. Always consult a healthcare professional. Terms
Doctors gave tiny premature babies either a daily vitamin D pill or one big shot to fix their low vitamin D levels.
Systematic Reviews & Meta-Analyses
Max 100Randomized Controlled Trials
Max 90Cohort Studies
Max 72Case-Control Studies
Max 58Cross-Sectional Studies
Max 44Case Reports & Case Series
Max 30Expert Opinion & Narrative Reviews
Max 554 / 90
Evidence Score
Participants are randomly assigned to treatment or control groups, minimizing bias. Considered the gold standard for testing whether an intervention causes an effect.
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Claims (6)
Before treatment began, people given vitamin D by mouth had the same average blood levels of vitamin D as people given vitamin D by injection.
Premature infants with vitamin D deficiency had an average blood vitamin D level of 13.20 ng/mL, which is classified as severe deficiency, showing that severe deficiency is common in this group.
In premature infants with low vitamin D levels, both a daily oral dose of 1,000 IU and a single injection of 15,000 IU raise vitamin D levels to a sufficient range within 15 days without altering blood calcium, phosphorus, or alkaline phosphatase levels.
Giving premature infants vitamin D by mouth or injection does not change their blood levels of calcium, phosphorus, or alkaline phosphatase within 15 days.
In premature infants with low vitamin D, taking 1,000 IU of vitamin D3 by mouth every day for 15 days leads to higher blood levels of vitamin D than receiving one 15,000 IU injection, even when starting from the same low level.