In cow liver cells, a chemical called acetate seems to turn off a key fat-making enzyme by flipping a molecular switch, and this only happens when another switch (called AMPK) is working.

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Pro

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Against

Evidence from Studies

Supporting (1)

11

Community contributions welcome

11

Acetic Acid Activates the AMP-Activated Protein Kinase Signaling Pathway to Regulate Lipid Metabolism in Bovine Hepatocytes

Cross-Sectional Study

Animal

2013

The study shows that acetate turns on a cellular switch (AMPK) in cow liver cells that slows down fat production by turning off a key fat-making enzyme, and this effect goes away if you block the switch—just like the claim says.

Contradicting (0)

0

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No contradicting evidence found

Gold Standard Evidence Needed

According to GRADE and EBM methodology, here is what ideal scientific evidence would look like to definitively prove or disprove this specific claim, ordered from strongest to weakest evidence.

Source Study

Acetic Acid Activates the AMP-Activated Protein Kinase Signaling Pathway to Regulate Lipid Metabolism in Bovine Hepatocytes

Score: 11

DOI: 10.1371/journal.pone.0067880

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