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v1
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Back to Study: Methylene blue improves mitochondrial respiration ...
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Analysis v1
Strong Support

Adding a tiny amount of methylene blue to heart cell power plants makes them use oxygen more efficiently, no matter what fuel they're burning.

10
Pro
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Against

Evidence from Studies

Supporting (1)

10

Community contributions welcome

10

Methylene blue improves mitochondrial respiration and decreases oxidative stress in a substrate-dependent manner in diabetic rat hearts.

Cohort Study
Animal
2017 Nov

The study found that a tiny amount of methylene blue helped heart mitochondria from both healthy and diabetic rats use oxygen better to make energy, no matter which fuel they were using.

Contradicting (0)

0

Community contributions welcome

No contradicting evidence found

Source Study

Methylene blue improves mitochondrial respiration and decreases oxidative stress in a substrate-dependent manner in diabetic rat hearts.

Score: 10
DOI: 10.1139/cjpp-2017-0074

Similar Assertions

A tiny amount of methylene blue helps heart cells make energy better, but too much actually hurts them — it’s a classic case of 'less is more'.

10
0
86%

Methylene blue makes heart cell power plants produce more harmful molecules when using one fuel (glutamate/malate), but less when using another (succinate), showing its effect depends on what the cell is burning.

10
0
85%

Adding methylene blue doesn’t change how well heart cell power plants can hold onto calcium, meaning it doesn’t protect against the pore that can cause cell death under stress.

10
0
78%

Methylene blue helps brain cells use oxygen more efficiently to make energy after they’ve been starved.

11
0
78%

Unlike some toxins, methylene blue doesn’t make harmful free radicals in brain cells after they’ve been starved.

11
0
72%