Adding methylene blue doesn’t change how well heart cell power plants can hold onto calcium, meaning it doesn’t protect against the pore that can cause cell death under stress.

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Pro

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Against

Evidence from Studies

Supporting (1)

10

Community contributions welcome

10

Methylene blue improves mitochondrial respiration and decreases oxidative stress in a substrate-dependent manner in diabetic rat hearts.

Cohort Study

Animal

2017 Nov

The study found that a tiny amount of methylene blue didn’t change how well mitochondria held onto calcium, which means it didn’t make the pore that can cause cell damage more or less likely to open — whether the rats were diabetic or not.

Contradicting (0)

0

Community contributions welcome

No contradicting evidence found

Source Study

Methylene blue improves mitochondrial respiration and decreases oxidative stress in a substrate-dependent manner in diabetic rat hearts.

Score: 10

DOI: 10.1139/cjpp-2017-0074

Similar Assertions

Adding a tiny amount of methylene blue to heart cell power plants makes them use oxygen more efficiently, no matter what fuel they're burning.

10

0

78%

A tiny amount of methylene blue helps heart cells make energy better, but too much actually hurts them — it’s a classic case of 'less is more'.

10

0

74%