Adding a drug called evolocumab to cholesterol-lowering statins can lower the chances of serious heart problems by 20% in people who already have heart disease.
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Evidence from Studies
Supporting (5)
79
Community contributions welcome
74
Evolocumab and Clinical Outcomes in Patients with Cardiovascular Disease
Randomized Controlled Trial
Human
2017 May 474
Evolocumab and Clinical Outcomes in Patients with Cardiovascular Disease
Randomized Controlled Trial
Human
2017 May 459
Proprotein convertase subtilisn/kexin type 9 inhibitors and small interfering RNA therapy for cardiovascular risk reduction: A systematic review and meta-analysis
Systematic Review With Meta-Analysis
Human
202348
Efficacy of lipid lowering therapy beyond statins to prevent cardiovascular events
Systematic Review With Meta-Analysis
Human
Contradicting (0)
0
Community contributions welcome
No contradicting evidence found
Gold Standard Evidence Needed
According to GRADE and EBM methodology, here is what ideal scientific evidence would look like to definitively prove or disprove this specific claim, ordered from strongest to weakest evidence.