Blocking eosinophil adhesion molecules with RGDS peptide reduces collagen and fibronectin gene activity in airway muscle cells to levels seen with healthy eosinophils.

Airway muscle cells grown with allergen-activated asthma eosinophils produce nearly 5 times more fibronectin gene activity than when grown with healthy eosinophils.

Airway muscle cells grown with allergen-activated asthma eosinophils produce over 5 times more collagen I gene activity than when grown with healthy eosinophils.