Scientists gave mice a supplement called nicotinamide riboside (NR) starting at 8 months old and found it didn't make them live longer or shorter compared to mice that didn't get the supplement.

13

Pro

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Against

Evidence from Studies

Supporting (1)

13

Community contributions welcome

13

17‐a‐estradiol late in life extends lifespan in aging UM‐HET3 male mice; nicotinamide riboside and three other drugs do not affect lifespan in either sex

Cohort Study

Animal

2021 May

This study tested nicotinamide riboside (a form of vitamin B3) in mice and found it did not make them live longer. The claim says NR didn't extend lifespan, and the study confirms exactly that - it didn't work for either male or female mice.

Contradicting (0)

0

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No contradicting evidence found

Gold Standard Evidence Needed

According to GRADE and EBM methodology, here is what ideal scientific evidence would look like to definitively prove or disprove this specific claim, ordered from strongest to weakest evidence.

Source Study

17‐a‐estradiol late in life extends lifespan in aging UM‐HET3 male mice; nicotinamide riboside and three other drugs do not affect lifespan in either sex

Score: 13

DOI: 10.1111/acel.13328

Similar Assertions

Scientists fed mice a special vitamin supplement called nicotinamide riboside in their food starting when the mice were middle-aged, then tracked how long they lived. The supplement didn't make the mice live longer.

13

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94%

A popular anti-aging supplement called nicotinamide riboside (NR) was given to mice to see if it could help them live longer, but the study found it didn't extend their lifespan at the doses tested.

13

0

85%