correlational
Analysis v1
Strong Support
Even though both muscle thickness and total lean mass went up after training, they didn’t change together in a predictable way—meaning one might not be a perfect stand-in for the other.
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Evidence from Studies
Supporting (1)
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Community contributions welcome
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Cluster sets and traditional sets elicit similar muscular hypertrophy: a volume and effort-matched study in resistance-trained individuals
Randomized Controlled Trial
Human
2025 JunThe study found that two different ways of lifting weights made muscles thicker and legs leaner in similar ways, but the amount of thickening didn’t match up perfectly with the amount of lean mass gain—suggesting they’re measuring different things, like water or other tissues, not just muscle.
Contradicting (0)
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Community contributions welcome
No contradicting evidence found