Even when accounting for differences in weight, fitness, and blood sugar, the more IGF-I went up, the better the muscle energy recovery — meaning IGF-I likely has a direct role.

Pro

Against

Evidence from Studies

Supporting (1)

Community contributions welcome

The effects of tesamorelin on phosphocreatine recovery in obese subjects with reduced GH.

Randomized Controlled Trial

Human

2014 Jan

This study found that when obese people with low growth hormone got a treatment that raised IGF-I levels, their muscles recovered energy faster after exercise — and this happened even after accounting for things like age, weight, and insulin levels, meaning IGF-I itself was likely the key factor.

Contradicting (0)

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No contradicting evidence found

Source Study

The effects of tesamorelin on phosphocreatine recovery in obese subjects with reduced GH.

Score: 61

DOI: 10.1210/jc.2013-3436

Similar Assertions

In people who took the placebo, IGF-I didn’t go up much, and their muscle energy recovery didn’t link to IGF-I — meaning the connection only showed up when the drug raised IGF-I.

91%

Even when accounting for factors like age, weight, and insulin levels, higher IGF-I still links to better muscle energy recovery in obese people with low growth hormone.

90%

Even when accounting for factors like age, weight, and insulin levels, higher IGF-I still links to better muscle energy recovery in obese people with low growth hormone.

88%

When IGF-I levels go up in obese people with low growth hormone, their muscle's ability to recover energy after exercise also improves, and this connection is statistically significant.

86%

When only looking at the best-quality muscle energy recovery data, higher IGF-I still links to better recovery in obese people with low growth hormone.

85%