When only looking at the best-quality muscle energy recovery data, higher IGF-I still links to better recovery in obese people with low growth hormone.
Scientific Claim
In a subset of high-quality phosphocreatine recovery data from obese adults with reduced growth hormone secretion, increases in insulin-like growth factor I (IGF-I) levels correlate with improvements in phosphocreatine recovery rate (ViPCr) (R=0.61, P=0.02).
Original Statement
“Sensitivity analyses using higher quality scans only (n = 15 pairs) confirmed the significant association between increases in IGF-I and improvement in ViPCr (R = 0.61; P = .02) (Supplemental Figure 1A published on The Endocrine Society's Journals Online web site at http://jcem.endojournals.org).”
Evidence Quality Assessment
Claim Status
appropriately stated
Study Design Support
Design supports claim
Appropriate Language Strength
association
Can only show association/correlation
Assessment Explanation
The study design supports correlational claims. The phrasing 'correlate with' correctly describes the relationship observed in the sensitivity analysis.
Evidence from Studies
Supporting (1)
The effects of tesamorelin on phosphocreatine recovery in obese subjects with reduced GH.