Changes in IGF-I levels don't relate to how much phosphocreatine is used up during exercise or muscle strength in obese people with low growth hormone.
Scientific Claim
In obese adults with reduced growth hormone secretion, changes in insulin-like growth factor I (IGF-I) levels are not significantly associated with changes in phosphocreatine depletion or maximal voluntary contraction (MVC) (P>0.10).
Original Statement
“There were no associations between the change in IGF-I with the change in PCr depletion or MVC (P > .10) (Table 2).”
Evidence Quality Assessment
Claim Status
appropriately stated
Study Design Support
Design supports claim
Appropriate Language Strength
association
Can only show association/correlation
Assessment Explanation
The study design supports correlational claims. The phrasing 'not significantly associated' accurately reflects the lack of statistical significance in the regression analyses.
Evidence from Studies
Supporting (1)
The effects of tesamorelin on phosphocreatine recovery in obese subjects with reduced GH.