When IGF-I levels go up in obese people with low growth hormone, their muscles recover energy faster after exercise, and this connection is statistically significant.
Scientific Claim
In obese adults with reduced growth hormone secretion, higher increases in insulin-like growth factor I (IGF-I) levels are associated with greater improvements in phosphocreatine recovery rate (ViPCr), with a correlation coefficient of 0.56 (P=0.01).
Original Statement
“We demonstrated a significant positive relationship between increases in IGF-I and improvements in PCr recovery represented as ViPCr (R=0.56; P=.01).”
Evidence Quality Assessment
Claim Status
appropriately stated
Study Design Support
Design supports claim
Appropriate Language Strength
association
Can only show association/correlation
Assessment Explanation
The study design supports correlational claims. The use of 'associated with' correctly reflects the observed relationship without implying causation between IGF-I and PCr recovery.
Evidence from Studies
Supporting (1)
The effects of tesamorelin on phosphocreatine recovery in obese subjects with reduced GH.