Even when people ate a lot of a specific trans fat found in dairy (CLA), their blood proteins stayed pretty much the same, so this type of fat probably doesn’t change how the body uses proteins in the blood.

Taking CLA supplements for three weeks doesn’t seem to change most common signs of inflammation in the blood, even though it might increase oxidative stress.

Even when people ate a lot of artificial trans fats—way more than normal—their blood proteins didn’t change much, so these fats might not mess with the body’s protein signals in a big way.

Even when people ate a very high amount of trans fats—either artificial or from dairy—their blood proteins didn’t change enough to be picked up by the method used, meaning this way of studying proteins might not be good for spotting diet effects.