Exercise increased the activity of a protein that helps blood vessels relax by more than double in the blood vessels of obese mice compared to sedentary mice.

Exercise boosted a key signaling protein in blood vessels by 37% in obese mice, which helps improve blood flow.

Exercise made a metabolic regulator in blood vessels 60% more active in obese mice compared to mice that didn't exercise.

Exercise reduced the levels of a key inflammatory protein in the blood vessels of obese mice by over 60% compared to mice that didn't exercise.

Exercise boosted levels of a protective anti-inflammatory protein in the blood vessels of obese mice by nearly five times compared to mice that didn't exercise.

Even without the surrounding fat tissue, exercise helped obese mice's blood vessels relax 17% better when exposed to a chemical that promotes widening.