Even without the surrounding fat tissue, exercise helped obese mice's blood vessels relax 17% better when exposed to a chemical that promotes widening.

When obese mice exercised, their blood vessels relaxed 19% better in response to a chemical that normally makes them widen, especially when the surrounding fat tissue was present.

Exercise increased the activity of a protein that helps blood vessels relax by more than double in the blood vessels of obese mice compared to sedentary mice.

Exercise made the fat cells around the blood vessels in obese mice about 4.1% smaller than in mice that didn't exercise.

Obese mice that exercised on a treadmill for 8 weeks weighed about 22.6% less than obese mice that didn't exercise.

Exercise boosted a key signaling protein in blood vessels by 37% in obese mice, which helps improve blood flow.