Obese mice that exercised on a treadmill for 8 weeks weighed about 22.6% less than obese mice that didn't exercise.

Exercise made the fat cells around the blood vessels in obese mice about 4.1% smaller than in mice that didn't exercise.

When overweight mice eat significantly less food, they lose body fat no matter if their diet is low in carbs, low in fat, or high in protein — the key is eating fewer calories overall.

Exercise boosted levels of a protective anti-inflammatory protein in the blood vessels of obese mice by nearly five times compared to mice that didn't exercise.

When obese mice exercised, their blood vessels relaxed 19% better in response to a chemical that normally makes them widen, especially when the surrounding fat tissue was present.

Even without the surrounding fat tissue, exercise helped obese mice's blood vessels relax 17% better when exposed to a chemical that promotes widening.