When obese mice exercised, their blood vessels relaxed 19% better in response to a chemical that normally makes them widen, especially when the surrounding fat tissue was present.

Even without the surrounding fat tissue, exercise helped obese mice's blood vessels relax 17% better when exposed to a chemical that promotes widening.

Exercise made the fat cells around the blood vessels in obese mice about 4.1% smaller than in mice that didn't exercise.

Exercise increased the activity of a protein that helps blood vessels relax by more than double in the blood vessels of obese mice compared to sedentary mice.

Obese mice that exercised on a treadmill for 8 weeks weighed about 22.6% less than obese mice that didn't exercise.

Exercise boosted a key signaling protein in blood vessels by 37% in obese mice, which helps improve blood flow.