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Strong Support
correlational
Analysis v1
History

Fat around the belly (visceral fat) is worse for your liver and metabolism than just being overweight overall—because it dumps harmful fats and chemicals straight into your liver.

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Evidence from Studies

Supporting (1)

1

Community contributions welcome

1

Non-alcoholic fatty liver disease and obesity: Biochemical, metabolic and clinical presentations

Narrative Review
2014 Jul 28

Contradicting (0)

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No contradicting evidence found

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Source Study

Non-alcoholic fatty liver disease and obesity: Biochemical, metabolic and clinical presentations

Score: 1
DOI: 10.3748/wjg.v20.i28.9330

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In men with belly fat, deep abdominal fat is linked to certain blood chemicals like PC 32:0, but under-skin fat isn't.

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Visceral adipose tissue releases bioactive molecules directly into the portal venous system, exposing the liver to elevated concentrations of free fatty acids and inflammatory cytokines.

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Fat around the organs dumps fat and inflammatory signals straight into the liver through a special blood pipe, where they can mess with liver cells and immune cells.

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Fat around the organs sends out fat molecules and inflammatory signals directly into the liver through a major blood vessel.

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Visceral adipose tissue is metabolically active and secretes pro-inflammatory cytokines that impair insulin signaling in liver, muscle, and brain tissues.

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